Given that individuals in Asia are classified as obese at a lower BMI threshold, the actual global obesity rate is very likely to be even higher (1). In the article recently published by Lingvay et al. titled “Obesity In Adults”, the authors thoroughly discussed the pathophysiology and impact of adult obesity, as well as its diagnosis, treatment goals, and clinical management. The article offers substantial guidance on clinical treatment strategies for adult obesity and provides insights for further research in this area (2). The concept of weight loss has typically been seen as a short-term plan and solution. Until recently, many people believed in a short-term modification of eating less and exercising as a solution for weight loss.
For Patients
- Aging, airway anatomy, weight regain, alcohol use, and underlying health conditions can all trigger OSA recurrence — even years after symptoms first resolved.
- “The more you lose weight, the more you want to exercise, you feel better. But it really is helpful to know that just that little bit of increase might be all you need.”
- The Mayo Clinic Diet is meant to be positive, practical, sustainable and enjoyable, so you can enjoy a happier, healthier life over the long term.
- Understanding the full picture helps patients protect their health long after the scale shows progress.
- While having a healthy role model can be a great way to stay motivated, being overly critical of yourself can set you back and may lead to unhealthy behaviors.
- If your BMI is 25 to 29.9, your weight is classified as overweight but not obese.
“Pescetarian diets are similar to a vegetarian diet but include fish and seafood,” Castro explains. Yet, even if you are leaning on these more processed vegan-friendly foods, you may still achieve weight loss. One study examined how processed foods affect weight loss in 244 adults who followed either a vegan or a regular diet for 16 weeks. Those who followed a vegan diet lost significantly more weight than the control group. Researchers found that reducing animal-based foods, whether unprocessed, minimally processed, or highly processed, was strongly linked to weight loss. Interestingly, eating processed plant-based foods did not lead to weight gain.
When you are ready to get started, explore these five steps to guide you to a healthier weight. To complement, not replace, your care, the WeGoTogether® app was developed by Novo Nordisk, the maker of Wegovy®, to support your patients as they work to lose weight and keep it off. #Observed data include only patients who had a body-weight assessment at week 72 (950 of 1,005 for Wegovy® HD 7.2 mg injection arm and 171 of 201 for placebo arm) and do not include all randomized patients. §The co-primary end point was percentage change in body weight for Wegovy® HD vs placebo.
Long-Term Weight Loss: More Than a Diet, It’s a Lifestyle
Sustainable weight management refers to a healthy amount of gradual weight loss that you can maintain without extreme tactics or emotional or physical harm. Also, don’t forget to look for supporters among your family, friends, and coworkers. You might share healthy recipes, meet up to exercise, or even start a weight loss program together. Or they could simply offer a listening ear when you’ve had a setback or are having trouble staying motivated. Focus on the loss of fat and aim to keep and even build muscle mass.
Hormonal Changes
Treatment depends on OSA severity (AHI score), symptom burden, airway anatomy, and individual preference. Mild recurrent OSA may be managed effectively with positional therapy, a mandibular advancement device, or lifestyle modifications. If symptoms return — even partially — a repeat formal sleep evaluation is essential. Self-assessment is not sufficient because many people underestimate their symptom severity.
TABLE 1. Discontinuation Strategies for Injectable Obesity Management Medications
If you try to change too many things at once, you may be setting yourself up for failure. Keeping a food record may be helpful short term for trying to identify eating patterns and behaviors. Logging what and when you eat along with how you feel and where you are when you eat them can help you identify patterns that may be contributing to weight gain or impeding your weight loss. Once you identify these patterns, you can take steps to modify the underlying behavior to create habits that are sustainable for a lifetime of health. Since the inception of the Part D program, CMS has interpreted the statutory exclusion of “agents when used for weight loss” to mean that a drug, when used for weight loss, is excluded from the definition of a covered Part D drug. This historical interpretation does not distinguish between use of a drug for treatment of individuals with obesity and individuals without obesity.
Patients who stayed on Wegovy® 2.4 mg achieved sustained results against weight regain1,4

Improve your digestion first to make your journey easier and possibly more successful. The increased activity happened as part of structured lifestyle programs that also included diet changes and behavioral counseling. Based on the latest clinical trials and real-world data, tirzepatide (Zepbound) currently stands out as the most effective FDA-approved prescription medication for weight loss.
Semaglutide is also approved to treat type 2 diabetes under the brand name Ozempic which may be a more familiar name to some patients. You might start with a supervised weight loss and exercise program. Ask your doctor to help you set personal goals and refer you to other professionals who can help.
Eat Mindfully
Whether you decide to follow a customized chronic weight management plan, try a chronic weight management pill, or simply start by making small daily changes, consistency is the key to success. Processed foods frequently contain detrimental fats, sugars, and calories devoid of nutritional value, which can impede weight loss. Minimize your packaged snacks, sugary beverages, and fast food intake to maximize success. It often results in reduced motivation and energy, making engaging in physical activity or maintaining a regular exercise routine challenging. It can lead to overeating as individuals turn to comfort foods for relief, disrupt sleep patterns, and affect hormones that regulate appetite, leading to increased hunger and cravings.

Common Short-Term Side Effects of Semaglutide Therapy
Everyday activities include climbing stairs, smart fitness recommendations grocery shopping, or cleaning the house. Being unable to perform everyday activities is called functional limitation. Physically active middle-aged or older adults have a lower risk of functional limitations than people who are inactive. Many people use food to help them deal with feelings of sadness, stress, or anxiety. People with obesity are at higher risk for mood and anxiety disorders.
Focus on Realistic Goals for Weight Loss
Being able to enjoy a small portion of a homemade dessert or indulging in a favorite holiday dish is part of having a healthy relationship with food. Making room for appropriate indulgences here and there will teach you self-control and keep you from feeling resentful of your new, healthy lifestyle. Keeping track of exactly what is going into your body is a great way to get healthy.
Fuel groundbreaking medical research!
In his free time, Dr. Vedala enjoys traveling with his wife, being a foodie, playing with his dogs, ballroom and Bollywood dancing, karaoke and keeping up with personal fitness. These programs apply only to self-pay patientsand are not covered by insurance. It works by blocking a digestive enzyme that breaks down fats in the GI tract, thus inhibiting the absorption of dietary fats. Interactions may occur during or within 14 days following the use of monoamine oxidase (MAO) inhibitors, sympathomimetics, alcohol, adrenergic neuron-blocking drugs, and possibly some anesthetic agents.